吴晶磊
发布部门:化学化工与生物工程学院       发布时间:2019-09-11


吴晶磊生物医学工程博士,东华大学化学化工与生物工程学院讲师,硕士生导师。20178月毕业于德克萨斯大学阿灵顿分校与德克萨斯大学西南医学中心。主持国家自然科学基金青年基金1项、东华大学中央高校自由探索项目1项,参与国家自然科学基金面上项目1项,发表SCI论文20多篇,获得授权发明专利1项。


主要研究方向:


1.  功能化细胞外基质天然生物材料的研究与应用

2.  组织工程与再生医学

 

主持或参与的主要项目


1.国家自然科学基金青年基金,可注射脱细胞基质/PRP水凝胶对半月板修复与再生的研究,319009492020.1-2022.12,主持

2.东华大学中央高校自由探索项目,载药仿生纳-微米纤维支架调控心肌细胞增殖与分化的机理研究,19D1105062019.1-2021.12,主持

3.国家自然科学基金面上项目,PLLACL气凝胶联合3D打印构建仿生气管及犬原位移植后长期存活的研究,819700912020.1-2023.12,参与

 

代表性论文


1. Wu J, Brazil B, McMahan S.R, Liao J, Hong Y. Heart valve tissue-derived hydrogels: preparation and characterization of mitral valve chordae, aortic valve, and mitral valve gels. J Biomed Mater Res Part B: Applied Biomater 2018; 107(5):1732-40.

2. Wu J, Ravikumar P, Nguyen KT, Hsia CCW, Hong Y. Lung protection by inhalation of exogenous solubilized extracellular matrix. Plos One 2017; 12:e0171165. (IF=2.776)

3. Wu J, Hong Y. Enhancing cell infiltration of electrospun fibrous scaffolds in tissue regeneration. Bioact Mater 2016; 1:56-64

4. Wu J, Ding Q, Dutta A, Wang Y, Huang Y-H, Weng H, Tang L, Hong Y. An injectable extracellular matrix derived hydrogel for meniscus repair and regeneration. Acta Biomater 2015;16:49-59.

5. Wu J, Huang C, Liu W, Yin A, Chen W, He C, Wang H, Liu S, Fan C, Bowlin GL, Mo X. Cell infiltration and vascularization in porous nanoyarn scaffolds prepared by dynamic liquid electrospinning. J Biomed Nanotechnol 2014;10:603-14.

6. Wu J, Liu S, He L, Wang H, He C, Fan C, Mo X. Electrospun nanoyarn scaffold and its application in tissue engineering. Mater Letters 2012;89:146-9.

7. Feng B, Wang S, Hu D, Fu W, Wu J, Hong H, Domian I. J, Li F, Liu J. Bioresorbable electrospun gelatin/polycaprolactone nanofibrous membrane as a barrier to prevent cardiac postoperative adhesion. Acta Biomater 2019; 83:211-20

8. Ma L1, Wang X1, Wu J1, Zhang D, Zhang L, Song X, Hong H, He C, Mo X, Wu S, Kai G, Wang H. Polyethylenimine and sodium cholate-modified ethosomes complex as multidrug carrier for the treatment of melanoma through transdermal delivery. Nanomedicine 2019: doi: 10.2217/nnm-2018-0398.

9. Huang Y, Zhou J, Wu J, Hong Y, Tang L. An optical probe for detecting chondrocyte apoptosis in response to mechanical injury. Scientific Reports: 2017; 7: 10906

10. Zheng X, Wang W, Liu S, Wu J, Li F, Cao L, Liu X, Mo X, Fan C. Enhancement of chondrogenic differentiation of rabbit mesenchymal stem cells by oriented nanofiber yarn-collagen type I/hyaluronate hybrid. Mater Sci Eng C Mater Biol Appl 2016;58:1071-6.

11. Xu C, Huang Y-H, Wu J, Tang L, Hong Y. Triggerable degradation of polyurethanes for tissue engineering applications. ACS Appl Mater Interfaces 2015;7:20677-88.

12. Jeffords ME1, Wu J1, Shah M, Hong Y, Zhang G. Tailoring material properties of cardiac matrix hydrogels to induce endothelial differentiation of human mesenchymal stem cells. ACS Appl Mater Interfaces 2015;7:11053-61.

13. Liu S1, Wu J1, Liu X1, Chen D, Bowlin GL, Cao L, Liu X, Mo X, Fan C. Osteochondral regeneration using an oriented nanofiber yarn-collagen type I/hyaluronate hybrid/TCP biphasic scaffold. J Biomed Mater Res A 2014; 103:581-592.

14. Xu Y, Dong S, Zhou Q, Mo X, Song L, Hou T, Wu J, Li S, Li Y, Gan Y, Xu J. The effect of mechanical stimulation on the maturation of TDSCs-poly(L-lactide-co-caprolactone)/collagen scaffold constructs for tendon tissue engineering. Biomaterials 2014;35:2760-72.

15. Xu Y, Wu J, Wang H, Li H, Di N, Song L, Li S, Li D, Xiang Y, Liu W, Mo X, Zhou Q. Fabrication of electrospun poly(L-lactide-co-epsilon-caprolactone)/collagen nanoyarn network as a novel, three-dimensional, macroporous, aligned scaffold for tendon tissue engineering. Tissue Eng Part C, Methods 2013;19:925-36.

16. Zhang K, Wu J, Huang C, Mo X. Fabrication of silk fibroin/P(LLA-CL) aligned nanofibrous scaffolds for nerve tissue engineering. Macromol Mater Eng 2013;298:565-74.

17. Yin A, Zhang K, McClure MJ, Huang C, Wu J, Fang J, Mo X, Bowlin GL, Al-Deyab SS, El-Newehy M. Electrospinning collagen/chitosan/poly(L-lactic acid-co-caprolactone) to form a vascular graft: Mechanical and biological characterization. J Biomed Mater Res A 2013;101:1292-301.

18. Huang C, Niu H, Wu J, Ke Q, Mo X, Lin T. Needleless electrospinning of polystyrene fibers with an oriented surface line texture. J Nanomater 2012;2012:1-7.

19. Li J, Liu W, Yin A, Wu J, Mohamed S, El-Newehy H, Mo X. Nano-yarns reinforced silk fibroin composites scaffold for bone tissue engineering. J Fiber Bioeng Informatics 2012; 5:169-79.

20. Liu J, Wu J, Fan L, He C, Wang H, Mo X. The characterization of poly(lactic-co-glycolic acid)/silk fibroin blend nanofibrous mats with the methanol vapor treatment. Integrated Ferroelectrics 2011;128:91-6. 


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东华大学化学化工与生物工程学院