Coatings for Medical Products for better Compatibility
发布部门:化学化工与生物工程学院       发布时间:2019-11-26


Prof. Rumen Krastev studied chemistry and focused on Thin Layers and Neutron reflectometry. He got his PhD degree in Physical Chemistry of Dispersed Systems and had worked as Group leader Max-Planck Institute of Colloids and Interfaces form 2002to 2008. Since 2008 he worked for Group leader NMI, Reutlingen – Biomaterials and coatings for medical devices. Since 2013 he became to be the faculty of Applied Chemistry, Reutlingen University. And he took the charge of the  dean of the faculty in 2019.


A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which includes an amphiphilic polymer or copolymer, in embodiments polyethylene glycol, having a substantially water-insoluble therapeutic agent dispersed therein. In some embodiments, the coating may also include iodine. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.