Peiran Chen

Peiran Chen


CURRICULUM VITAE


Professor, College of Chemistry and Chemical Engineering, Donghua University



Name:Peiran Chen  Orcid (mandatory): 0009-0002-7242-1990

Address:2999 North Renmin Road, Shanghai, 201620, P.R. China

E-mail: prchen@dhu.edu.cn

Phone: 0086-21-67792654;

Date of birth:June 18, 1973

Citizenship:P. R.China

Sex: Male


  1. Education/Training

Title or activity

Starting and completion date

Institution/ Entity

B.Sc. degree

1991.7-1995.7

Institute of Fine Chemical Engineering, East China University of Science and Technology.

Ph.D. degree

1998.7-2003.7

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

Postdoctoral research fellow

2003.10-2005.10

National Institute of Diabetes, Digestive and Kindey Diseases, (NIDDK), National Institute of Health (NIH), USA


Peiran Chen obtained his Ph. D in 2003 from Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences under the supervision of Professor Guoqiang Lin and Professor Zuyi Li, working on the bio-catalyzed enantioselective synthesis of chiral cyanohydrins as chiral building blocks. He then joined Dr. Kenneth A. Jacobson(NIDDK, NIH)as postdoctoral research fellow(2003-2005), working on the synthesis of adenosine analogies as antagonist of a2 acceptor. In late 2005, he joined the College of Chemistry and Engineering, Donghua University.


Research Interests:

  • The synthesis of anomerically stereo-controlled Ferrier glycosylation reaction;

  • The synthesis of chiral secondary alcohols and α-Cyanohydrins with dynamic kinetic resolution(DKR);

  • The design, preparation and evaluation of new photodynamic drugs


Selected publications:

1. Hong-Yu Liang, Ying Jiang, Yi-Jia Yan, Lu-Qi Wang, Pei-Ran Chen*, and Zhi-Long Chen*. Synthesis of novel meso-tetraphenyltetrabenzoporphyrins and evaluation of their photodynamic anticancer activities. ACS Omega, 2025 10(11):11119-11127.

2. Hong-Yu Liang, Ying Jiang, Zhi-Bing Song, Ning Cao, Pei-Ran Chen*, Yi-Jia Yan, Zhi-Long Chen*. Preparation and pharmacological evaluation of A3B-type tetraphenyltetrabenzoporphyrins for photodynamic anti-tumor therapy. Journal of Photochemistry & Photobiology, A: Chemistry, 2024, 455, 115759.

3. Hong-Yu Liang, Ying Jiang, Zhi-Bing Song, Tabbisa Namulinda, Pei-Ran Chen*, Zhi-Long Chen*, and Yi-Jia Yan. Synthesis and evaluation of novel meso-tetraphenyltetrabenzoporphyrins for photodynamic therapy. ACS Medicinal Chemistry Letters. 2024, 15, 1109−1117.

4. Peiran Chen*, Xueqi, Dai.  Site-specific synthesis of 3-Se-1,2-unsaturated glycosides with R-Se-Se-R as the nucleophile precursors promoted by InCl3/Hf(OTf)4. Tetrahedron Letters. 2021, 86, 153454.

5. Peiran Chen*, Saisai Guo, Junfeng Zuo, Ruiji Chua, XuHe, Guijiang Zhu. Synthesis of 3-S- and 3-Se-glycals by using R-S-S-R and R-Se-Se-R as the nucleophile precursors promoted by Hf(OTf)4 and the temperature dependent formation of the above-mentioned 3-S- and 3-Se products. Tetrahedron Letters. 2020, 61, 151648.